Monitoring of the aging of magnetic nanoparticles using Mössbauer spectroscopy

Magnetic nanoparticles made of magnetite have the advantage to be biocompatible and to have a good saturation magnetisation. In this work we show that magnetite nanoparticles change their magnetic and chemical characteristics over time, depending on their storage conditions. To determine the oxidation state of the iron in the core of the nanoparticles Mössbauer spectroscopy was used at 4.2 K. This method is very accurate, especially in distinguishing maghemite and magnetite. The nanoparticles prepared by a co-precipitation method and peptized using acidic media had a core diameter of 5–7 nm. The aging process was monitored until the core was completely oxidised to maghemite and no further change occurred. The greatest change in the magnetite content of the particles was seen during the first 12 h after preparation. To preserve the good magnetic characteristics of magnetite nanoparticles a coating that prevents oxidation is therefore essential. Our results show that the point in time of the characterisation of small magnetic nanoparticles is crucial for the results. Even though magnetite nanoparticles have been formed nearly stoichiometrically, their chemical properties change over time. & 2014 Elsevier B.V. All rights reserved.